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Heavy Drinking Expedites the Brain’s Quiet Unraveling and Destruction
From:
Dr. Patricia A. Farrell -- Psychologist Dr. Patricia A. Farrell -- Psychologist
For Immediate Release:
Dateline: Tenafly, NJ
Saturday, October 25, 2025

 

From memory loss to mood instability, science shows alcohol’s damage runs deeper than most imagine.

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People share different stories about their drinking habits that range from celebrating friendships to finding comfort and using alcohol for relaxation. In fact, many people with social anxiety disorder are particularly prone to excess alcohol consumption because it helps them relax.

The glass becomes dangerous when it reaches the brain’s maximum capacity because it then transforms into something shocking and undesirable: brain damage. Heavy drinking creates this brain damage through its ability to harm memory functions, emotional responses, and personality traits. Many of us have witnessed this sudden change in personality when someone is “over the line” in their drinking — and it can be pretty upsetting for everyone. But the damage process develops gradually as it transforms brain operations, and that is one of its most dangerous aspects.

The brain contains billions of nerve cells, which exchange information through electrical and chemical signals. These functional systems become disrupted when alcohol enters. Now, brain signal transmission slows as myelin, the fatty coating, deteriorates, and neurotransmitter chemical balance is disrupted.

The brain experiences permanent damage in its judgment, memory, and movement control areas because of prolonged interference. The three brain areas that suffer the most damage include the frontal lobes, which handle decision-making and impulse control, the hippocampus, which stores memory, and the cerebellum, which controls movement and balance.

Brain cells start to shrink and die when alcohol repeatedly attacks these brain areas. MRI scans of heavy drinkers who drink for extended periods show brain tissue reduction which indicates neurons and their connections disappear at rates that exceed brain repair capabilities.

The progression of Alzheimer’s dementia becomes faster when people consume excessive amounts of alcohol. Research indicates that drinking more than 28 alcoholic beverages weekly leads to higher chances of developing Alzheimer’s disease and dementia. The brain cells die because alcohol creates conditions that allow toxic proteins beta-amyloid plaques and tau tangles to accumulate.

I recall an associate who was in alcohol research receiving a plea from a very famous Hollywood actor regarding help with her husband, who was alcoholic. He told me, “There was nothing we could do because alcohol somehow crosses the blood-brain barrier.” Perhaps it may not cross the BBB, but it has its effect inside the brain as noted.

The brain undergoes atrophy, leading to physical shrinkage that affects areas involved in storing new memory information and other functions as noted above.

A South Korean research study monitored 4 million participants to discover that heavy drinking significantly raised dementia development risks. But research also indicates that people who decrease their drinking from heavy to moderate levels experience lower dementia risk.

Other research has proven contradictory in that it has indicated a low level of alcohol consumption weekly may improve an individual’s cognitive functioning. How, therefore, are we to evaluate this research and understand that there may be methodological problems here. Whether or not we should drink any alcohol or a moderate amount weekly still seems to be an unresolved issue. It leaves us with no definitive answer. The best choice, obviously, would be not to drink alcohol at all.

The Nervous System Faces Damage

The development of alcoholic neuropathy occurs when people drink heavily because their nerve fibers in hands and feet and legs deteriorate. The condition produces three main symptoms, which include numbness and tingling, burning pain, and muscle weakness. The toxic nature of alcohol together with its ability to deplete vitamin B1 (thiamine) from the body causes this damage to nerve tissue.

There is another quite serious condition that must be discussed. The condition known as Wernicke-Korsakoff syndrome, or “wet brain,” develops when thiamine B1 levels are severely low. Confusion, unsteady walking, and strange eye movements are early signs.

We’ve seen odd eye movements, especially in drug abusers. This is an effect on normal eye movement known as nystagmus. Drug abusers show exaggerated nystagmus movements, unlike the rest of us who have extremely subtle movements.

Wernicke’s advances into permanent memory loss and makes new memory formation impossible when left untreated. It also demonstrates how excessive drinking creates permanent damage to the nervous system.

The cerebellar degeneration process damages the brain area that controls coordination functions. People who develop this condition show unsteadiness while speaking with slurred words and experience difficulties walking, even when they have not consumed alcohol. So, it’s not the movement of a person who is drunk, but of a person who is sober and not drinking at that moment that shows the permanent brain damage already established.

Heavy drinking causes changes to mental health through its impact on emotional processing systems. The initial effect of drinking alcohol creates a sense of relief because it helps people manage their anxiety and sadness. The brain then develops new patterns of operation over time which result in decreased production of serotonin and dopamine levels. It now undergoes a rapid decrease in serotonin and dopamine levels after alcohol consumption ends, resulting in depression, anxiety, and irritability.

The Royal College of Psychiatrists indicates that heavy drinking leads to higher chances of developing depression, panic disorder, and impulsive behavior problems. Some people develop severe anxiety symptoms, phobias, and post-traumatic stress disorder symptoms. This combination of alcohol consumption and mental illness creates a destructive pattern where people use alcohol to manage their distress, which leads to increased mental health problems. It is, in fact, a vicious cycle.

The combination of heavy drinking with mental health issues creates an extremely dangerous situation for people between 13 and 24 years old. The brain continues its development process until it reaches age 25, as alcohol consumption disrupts the formation of new neural pathways. Early heavy drinking causes permanent damage to attention and learning abilities, and emotional control.

What’s Safe Drinking or Harmful Consumption?

Scientists struggle to establish what constitutes excessive drinking because people develop different levels of tolerance and their bodies process alcohol differently. Initially, research studies indicated that light to moderate drinking provided heart benefits and improved mental performance. Unfortunately, this research was misguided and methodologically impaired.

Research conducted since then demonstrates that any amount of alcohol consumption creates brain-related health risks. One study noted that alcohol consumption directly leads to dementia progression through a straight-line relationship. There exists no established threshold that guarantees safety.

The public health guidelines recommend that men should not exceed 14 drinks per week, and women shouldn’t exceed a lower amount, but heavy drinkers with specific health conditions face increased risks. The best approach for brain health protection involves either drinking in moderation or staying completely sober when heavy drinking has already caused damage. This has also raised the question of whether someone who previously drank heavily can return to moderate drinking of alcohol. Would that seem wise, especially if the person had pre-existing anxiety difficulties?

The Human Aspect of Recovery Work

Statistics represent individual people who started drinking for relaxation purposes, socializing, and to escape their emotional pain. All of these issues can best be addressed in a means other than alcohol consumption.

Recovery, however, remains achievable for people who want to stop drinking. The brain shows exceptional healing potential when patients receive proper nutrition, thiamine supplements, mental health treatment, and medical care. There can be better function in memory, mood, and nerve system operation for people who decrease their alcohol consumption, even if they don’t stop drinking altogether. But should anyone want to take a chance with drinking alcohol when we know how destructive it is to the brain? Not everyone is going to have brain repair, and that is a serious concern.

Medical professionals, together with therapists and family members provide essential support, which enables people to achieve lasting recovery. Full utilization of all resources can help the brain start to rebuild its neural pathways through exercise, social interaction, creative activities, and proper sleep patterns.

Think Before You Drink

Consider several important factors noted here. Memory functions as an integral part of personality and balance, which together form an interconnected system. Heavy drinking causes the brain to lose its ability to function as a single unit by damaging both neural pathways and mental stability. The regular consumption of excessive alcohol leads to damage of both mental processes and emotional states.

Unfortunately, many cultures believe that celebrations are associated with drinking alcoholic beverages. But even in celebration, excessive alcohol consumption is a danger that no one should want to risk. You might enjoy hiking, but would you want to stand at the edge of a cliff and depend on it not breaking off and sending you tumbling to your death?

The research is in, and most of it points to limiting or not consuming alcohol at all. You make the choice. It’s your life and your brain, and everyone around you will be affected by the choices you make in this particular area.

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News Media Interview Contact
Name: Dr. Patricia A. Farrell, Ph.D.
Title: Licensed Psychologist
Group: Dr. Patricia A. Farrell, Ph.D., LLC
Dateline: Tenafly, NJ United States
Cell Phone: 201-417-1827
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